Biomodel

Virtual Laboratories

Cybertory: virtual molecular biology lab

Access:

enter Enter the virtual laboratory.

enterSequence analysis - Direct link to the tools (transcription-translation, sequence pattern search, sequence massager)

página General instructions for the use of Cybertory.

Features:

Possible applications:

Workbooks:

  1A 1B 1C 1D 2 3 4 5 6
using electrophoresis sí sí sí   sí sí sí sí sí
using restriction enzymes sí sí     sí        
using PCR           sí sí sí sí

páginaGeneral instructions for the use of Cybertory.

  1. Genetic diagnosis; βAS polymorphism in the beta globin gene, responsible for drepanocytosis and drepanocytic anaemia (sickle cell anaemia):
    1A pdf Testing restriction enzymes for the analysis of this polymorphism by RFLP. doi:10.5281/zenodo.1299796
        mostrarSome enzyme sets suitable for this practical.
    1B pdf Molecular genetic diagnosis of the polymorphism by RFLP. doi:10.5281/zenodo.1299811
    1C pdf DNA sequencing to analyse this polymorphism (dideoxynucleotides method). doi:10.5281/zenodo.1299816
    1D pdf Introduction to genomic sequence databases and analysis of sequences related to this polymorphism. doi:10.5281/zenodo.1299825
  2. pdf Forensic analysis: genetic identification of individuals using RFLP. doi:10.5281/zenodo.1299843
  3. pdf Paternity test using multiplex PCR on STR markers (CoDIS). https://doi.org/10.5281/zenodo.1299837
  4. pdf Genetic diagnosis, personalised medicine. Identification of polymorphic variants on cytochrome P450 (CYP2C9), using multiplex PCR. doi:10.5281/zenodo.1299846
  5. pdf Genetic diagnosis of celiac disease. Identification of polymorphic variant associated to celaic disease, using multiplex PCR on the DQ2 and DQ8 markers. doi:10.5281/zenodo.1299854
  6. pdf Dairy product analysis. Identification of the source of milk (cow, sheep or goat) by analysis of mitochondrial DNA. doi:10.5281/zenodo.1299860

Simulation of celulose acetate electrophoresis of proteins

Features:

Possible applications:

Access:

Access the simulator entrada for serum proteins and entrada for LDH isoenzymes.

Simulation of SDS-PAGE electrophoresis of proteins

Features:

Possible applications:

Workbooks:

These are integrated into the simulation page:

mostrarPractice problem 1: influence of the voltage applied.

mostrarPractice problem 2: influence of the acrylamide concentration.

mostrarPractice problem 3: estimation of molecular mass of the unknown proteins.

mostrarPractice problem 4: determination of quaternary structure (I).

mostrarPractice problem 5: determination of quaternary structure (II).

Access:

entrada Acces the simulator.

Simulation of column cromatography of proteins

Features:

Possible applications:

Access:

entrada Access the simulator.

Working plans:

Project: design of problem-solving activities using the simulator.

Other labs

These are ready but not yet translated into English. You can check the Spanish versions or, if you are interested on them, for setting an English translation.