The “wobbling” hypothesis was proposed to explain how a single anticodon may interact with several different codons, which differ on their third base.
    This consists on the 3^rd (3') and 2^nd (middle) bases in the anticodon recognising the respective bases, 1^st (5') and 2^nd (middle), in the codon in a strict way, according to Watson and Crick pairing rules (A-T, C-G), while the first base in the anticodon (5') is less selective and may establish with the 3^rd base in the codon (3') either a Watson-Crick pair or, by a slight shift, a different pair. This allows

• G to pair with either C or U in the codon
• U to pair with either A or G in the codon
• I (inosine) to pair with either A, C or U in the codon