DNA through several consecutive zinc finger motifs.
motif, consists in this case of a peptide segment in alpha helix
and two in antiparallel beta sheet,
in which there are 4 amino acids (2 Cys and 2 His) whose sidechains coordinate the Zn2+ ion;
this kind of zinc finger is so called C2H2.
The atoms coordinating Zn (N in His
and S in Cys) are highlighted.
2H2 zinc finger motifs in the same polypeptide chain.
zinc finger motif.
In this case, the protein has a single zinc finger but forms a dimer
when bound to DNA.
Zn2+ ions, each one coordinated by a helix and a loop,
through the sidechains of 4 cysteines
for each Zn ion.
This kind of motif is called a C4 zinc finger.